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Poster 306:

Beyond Saturday Night: A Case Series of Radial

Neuropathy in the Arm Diagnosed by Ultrasound in

Conjunction with Electrodiagnosis

Austin C. Myers, MD MBA (Vidant Rehab Ctr/East Carolina Univ/Brod),

Eric Morrison, MD, MSc, John Norbury, MD, Siena Ona, MD

Disclosures:

Austin Myers: I Have No Relevant Financial Relationships

To Disclose

Case/Program Description:

Three patients presented for evaluation

of wrist drop. Patient 1 was a 15-year-old boy who awoke with a wrist

drop and numbness following surgical repair of a humerus fracture.

Patient 2 was a 58-year-old woman who awoke with wrist drop asso-

ciated with a bruise on her triceps and no history of trauma. Patient 3

was a 61-year-old man who awoke with a wrist drop following crutch

use and recent weight loss.

Setting:

Outpatient EMG Clinic.

Results:

Patient 1 had reduced radial motor and sensory amplitudes

on nerve conduction studies (NCS); Neuromuscular ultrasound (NMUS)

revealed a surgical screw impinging on the nerve at the spiral groove.

Patient 2 had normal radial NCS and reduced recruitment in the

extensor digitorum communis; NMUS revealed increased hypo-

echogenicity and caliber of the radial nerve at the exit of the spiral

groove in direct contact with a hematoma. Patient 3 had reduced

amplitude of the radial motor response with a normal radial sensory

response, NMUS showed increased nerve swelling at the spiral groove

on ultrasound.

Discussion:

Radial neuropathy at the spiral groove (Saturday Night

Palsy) can be a challenging diagnosis based on electrodiagnosis alone

because mild lesions can result in normal nerve conduction studies and

severe lesions result in non-localizing axon loss pathology. Addition-

ally, fascicular sparing can lead to erroneous localization (such as in

case 3 where the lesion is at the spiral groove, but sensory fibers were

spared). NMUS also revealed radial nerve pathology in this case series

that has not been described previously in the literature (non-traumatic

hematoma in case 2).

Conclusions:

Neuromuscular ultrasound can be a powerful compli-

ment to electrodiagnosis in localizing radial neuropathies and deter-

mining etiology.

Level of Evidence:

Level V

Poster 307:

Non-Rhythmic Recurrent Shaking After Right Basal

Ganglia Stroke: A Case Report

Aaron A. Hanyu-Deutmeyer, DO (Marianjoy Rehab Hosp),

Padma K. Srigiriraju, MD

Disclosures:

Aaron Hanyu-Deutmeyer: My spouse/partner has a rela-

tionship with Allergan Speakers bureau, My spouse/partner has a

relationship with Allergan provided Botox for injection

Case/Program Description:

A 73-year-old female patient with history

of prior stroke with residual left sided weakness presented to the ED

with “spasms” on her left side. She was noted to have non-rhythmic

shaking movements that lasted 2-5 seconds that would then recur

every 10-30 seconds. EEG showed no evidence of seizure, but MRI

showed evidence of acute infarct in the right basal ganglia.

Setting:

Tertiary care center and acute rehabilitation hospital.

Results:

Recurrent movements were captured on EEG with no evi-

dence of epileptiform activity. The patient was diagnosed with hem-

ichorea-hemiballism as a result of the basal ganglia stroke. Her

rehabilitation course was further complicated by residual deficits from

a previous stroke, and cerebral amyloid angiopathy with micro-

hemorrhages on MRI. The patient’s hemiballism was most apparent

during periods of stress, but she showed significant improvement in her

hemiballism with standard therapies. The patient made slow but

sustained progress, improving from a total assist to contact guard

assist at the time of discharge.

Discussion:

Hemiballism-hemichorea is an extremely rare neurolog-

ical condition with an incidence of 0.45/100000. It is caused by a

decrease in activity in the subthalamic nucleus most often from

stroke. However, due to this patient’s presentation and prior deficits,

stroke was not initially part of the differential diagnosis. This patient

had significant risk factors for stroke including diabetes, age, hyper-

tension. While able to participate in standard therapies for stroke,

medically due to her cerebral amyloid angiopathy, the risk of hemor-

rhage had to be carefully weighed against the risk of recurrent

ischemia.

Conclusions:

Post-stroke hemiballism-hemichorea causes profound

effects to a patient’s function. With an initial presentation that can

appear significantly different from a typical stroke, the spastic

movements can cause not only physical and emotional distress to the

patient but potentially continued long term deficits if not properly

identified and treated as a stroke.

Level of Evidence:

Level V

Poster 308:

West Nile Virus Encephalitis in an Immunosuppressed Patient

Who Presents to Rehabilitation: A Case Report

Joseph A. Wong, MD (George Washington University School of Med,

Edison, New Jersey, United States), Brian D. Greenwald, MD, FAAPMR

Disclosures:

Joseph Wong: I Have No Relevant Financial Relationships

To Disclose

Case/Program Description:

A 50-year-old woman status-post renal

transplantation and diagnosed with West Nile virus (WNV) encepha-

litis. Patient is status-post renal transplantation 13 years ago with

chronic rejection and maintained on immunosuppressive therapy who

initially presented with fever, abdominal pain, and lethargy that

quickly progressed to severe encephalopathy. Laboratory studies

revealed severe anemia and uremia, with no improvement of mental

status after urgent hemodialysis. Lumbar puncture revealed lym-

phocytic pleocytosis, and an exhaustive infectious work-up revealed

a positive WNV polymerase chain reaction test. Magnetic resonance

imaging of the brain showed acute cerebellitis. Management was

supportive with the intention to minimize immunosuppressive ther-

apy while trying to maintain the allograft transplant. Patient was

transferred to an acute inpatient brain trauma unit for comprehen-

sive rehabilitation.

Setting:

Academic acute inpatient rehabilitation facility.

Results:

Initial rehabilitation evaluation demonstrated impaired

arousal and inconsistent one-step command following. Maximum

assistance, verbal and tactile cues were required for sitting balance.

Patient displayed ataxic dysarthria, aphasia, persistent vertical

nystagmus, neuromuscular and motor impairments. The patient was

provided with comprehensive medical support and interdisciplinary

inpatient rehabilitation. Despite her ongoing medical complexities,

she showed significant improvements during her rehabilitation course.

Discussion:

WNV encephalitis presents in less than one percent of all

people infected with a ten percent mortality rate. Research suggests

that immunocompromised subjects may have a prolonged period of

viremia, depressed humoral response, increased severity and exten-

sion of pathology, and higher mortality rates. Limited case reports also

suggest the effectiveness of immunosuppression reduction without the

compromise of allograft outcomes. This case report adds to the dearth

of literature regarding treatment, rehabilitation, and outcomes of

immunocompromised patients with WNV encephalitis.

Conclusions:

This case presents the acute rehabilitation course of a

patient with WNV encephalitis, a diagnosis rarely seen in immuno-

compromised patients.

Level of Evidence:

Level V

S229

Abstracts / PM R 9 (2017) S131-S290