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symptoms. Results suggest that the CTMD may have effects that

continue post-treatment. Bilateral CTS patients may respond differ-

ently to treatment than unilateral CTS patients. An extended, ran-

domized, placebo-controlled study is proposed to further investigate

this technology.

Level of Evidence:

Level IV

Poster 9:

The Synergistic Effect of Antibacterial Photodynamic

Therapy and Carbapenem to Extended Spectrum Beta

Lactamase (ESBL)

Escherichia Coli

Yose Waluyo (Hasanuddin University, Makassar, Indonesia),

Firdaus Hamid

Disclosures:

Yose Waluyo: I Have No Relevant Financial Relationships

To Disclose

Objective:

To see the synergistic effect of LLLT and antibiotics to

ESBL

E coli

.

Design:

Bacterial strains including ESBL

Escherichia coli

were sus-

pended in saline solution, after that the suspension were spread on the

surface of petri plates, planting ertapenem antibiotic disc at the petri

plate and incubated at 37

o

C for quantification of colony forming unit.

One plate we give laser irradiation to the plate with antibiotics and

another only using antibiotics plate without laser. The clear zone

diameter was measured. Bacterial strains from this petri disc sus-

pended in the new saline solution and repeated 3 time in 3 days.

Setting:

Microbiology department, Faculty of medicine, Hasanuddin

University.

Participants:

ESBL

E coli

.

Interventions:

Bacterial strains including ESBL

E coli

were suspended

in saline solution, the density of the suspension is compared to the 0.5

McFarland turbidity standard, after that the suspension was spread on

the surface of petri plates, exposed to laser irradiation with (Four

670nm LED + Five 850nm Laser) diode specification at fluences of 0 J/

cm

2

(control), 2 J/cm

2

, planting ertapenem and meropenem antibiotic

disc at the petri plate and incubated at 37

o

C for quantification of

colony forming unit. After 24 hours the clear zone diameter measured.

Bacterial strains from this petri disc suspended in the new saline so-

lution and do the same thing above until 3 days and repeated 3 times.

Main Outcome Measures:

We measured the clear zone.

Results:

Laser irradiation increasing the sensitivity of ertapenem from

32 mm (control) to 33 mm at day 1, 34 mm at day 2, and 35 mm at day

3 where the clear zone of control still the same as day 1.

Conclusions:

The increasing of clear zone diameters of Ertapenem at

the irradiation petri plate showed that the sensitivity of antibiotic

increase. That indicating synergistic of LLLT and Carbapenem anti-

biotic, especially at the ertapenem.

Level of Evidence:

Level III

Poster 10:

Quality of Life Following Cardiac Rehabilitation on

Coronary Artery Disease Patients: Prospective

Longitudinal Cohort Study

Byung Joo Lee (Asan Medical Center, University of Ulsan College of

Medicine, Seoul, South Korea), Tae-Du Jung, MD PhD

Disclosures:

Byung Joo Lee: I Have No Relevant Financial Relation-

ships To Disclose

Objective:

To evaluate the effect of cardiac rehabilitation program

on quality of life (QOL) in patients after percutaneous coronary artery

intervention (PCI).

Design:

Propective Longuitudinal Cohort Study.

Setting:

The cardiac rehabilitation group had supervised exercise

three times a week for 8 weeks.

Participants:

Thirty patients who were 2-weeks post PCI, able to

attend supervised exercise, and had normal cognitive function,

participated in this study. Thirty men who didn’t have coronary artery

disease were recruited as a control group.

Interventions:

The cardiac rehabilitation program was based on the

symptom limited exercise tolerance test. It consisted of a 10-minute

warm up exercise, 45 minute main exercise, and a 5 minute cool down

exercise. It was performed three times a week for 8 weeks.

Main Outcome Measures:

The primary outcome, QOL, was assessed by

36-item short-form health survey (SF-36). It was performed at the

beginning and end of cardiac rehabilitation. SF-36 of control group was

also surveyed. Secondary outcomes were body mass index (BMI), waist-

hip ratio (WHR), maximal oxygen consumption (VO

2

max), maximal heart

rate(HRmax), resting heart rate(RHR), Borg ratings of perceived exertion

(RPE), rate pressure product (RPP), and maximal exercise time (ETmax).

Results:

After 8 weeks, the cardiac rehabilitation group showed statis-

tically significant improvements in physical function (PF), role physical

(RP), bodily pain (BP), vitality (VT), social functioning (SF), role emotional

(RE), mental health (MH), and mental component summary (MCS).

Compared to control group, patient group showed significantly low scores

on all summary scores and subdomains, except general health (GH), at the

initial assessment. However at 8 weeks, PF, BP, VT, MH, MCS, and Physical

Component Summary (PCS) showed no significant difference between the

two groups. In secondary outcomes, BMI, WHR, RHR, VO

2

max, MET,

ETmax, stage 3 RPE, MaxRPE, and stage 3 RPP showed improvements.

Conclusions:

Patients with coronary artery disease benefit greatly in

QOL and physical function from cardiac rehabilitation. Despite notice-

able improvement in patients’ physical function, mental component of

QOL showed more improvement than physical component.

Level of Evidence:

Level III

Poster 13:

Can Rehabilitation After Acute Myocardial Infarction

Delay the Onset of Depressive and Anxiety Disorder?

A Retrospective Cohort Study Based on a Nationwide

Population-Based Database

Sheng-Chun Kung, MD (Chi Mei Medical Center, Tainan, Taiwan,

Province of China), Wen-Chin Lin, MD, Kuo-Shu Yuan, PhD, Willy Chou,

MD

Disclosures:

Sheng-Chun Kung: I Have No Relevant Financial Re-

lationships To Disclose

Objective:

To investigate whether cardiac rehabilitation for patients

with acute myocardial infarction (AMI) delay the onset of anxiety or

depressive disorder.

Design:

Retrospective cohort study.

Setting:

We retrieved data from 1997 to 2011 using National Health In-

surance Research Database. The database included the data of onemillion

individuals and the coverage rate is as high as 99% of Taiwan’s population.

Participants:

Patients who were newly diagnosed with AMI from 1997

to 2011 were recruited. Then patients who received cardiac rehabili-

tation in 30 days after AMI were selected (n

¼

272). Patients without

rehabilitation were matched with the patients with rehabilitation

according to sex and age at a ratio of 1 to 5 (n

¼

1360).

Interventions:

Not applicable.

Main Outcome Measures:

The incidence and onset time of anxiety or

depressive disorder for 3 years after the AMI.

Results:

The Charlson Comorbidity Index score revealed no significant

difference between these two groups (p

¼

.29). So the disease severity

of these 2 groups were the same. There was no difference in the

incidence of anxiety or depressive disorders (Rehabilitation group:

5.15% vs without rehabilitation group: 5.66%, p

¼

.74). However,

regarding the time from an AMI attack to new onset of anxiety or

depressive disorder, the time of the rehabilitation group was signifi-

cantly longer (1.13 1.06 vs 0.52 0.63 years, p

¼

.0062).

Conclusions:

Cardiac rehabilitation can not reduce the incidence of

anxiety or depressive disorders after AMI, but it can significantly delay

the onset time of anxiety or depressive disorder after AMI attack.

Level of Evidence:

Level III

S145

Abstracts / PM R 9 (2017) S131-S290