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Poster 218:

Musculocutaneous Neuropathy Due to PICC Line

Insertion: A Case Report

Maria Janakos, MD (University of Louisville Physical Medicine,

Louisville, KY, United States), David Haustein, MD, Preeti Panchang, MD

Disclosures:

Maria Janakos: I Have No Relevant Financial Relation-

ships To Disclose

Case/Program Description:

A 55-year-old man with uncontrolled

diabetes mellitus developed a diabetic foot ulcer and osteomyelitis

requiring intravenous antibiotics. He underwent sonographically

guided PICC line placement using a 5-French catheter with radio-

graphic confirmation of the tip at the cavoatrial junction. The patient

recalls terrible pain and extensive ecchymoses of his right arm and

lateral thorax in the days following the procedure as well as weakness

with right elbow flexion and paresthesias over the lateral forearm. He

was seen 2 months later by a physiatrist at the VA hospital and found to

have weak right elbow flexion and diminished sensation in the right

lateral antebrachium; otherwise normal strength and sensation

throughout the bilateral upper limbs. An abbreviated electro-

diagnostic study was performed that day for further evaluation.

Setting:

VA hospital.

Results:

A limited EMG of the right upper limb demonstrated a right

musculocutaneous neuropathy at least proximal to the fascicles to the

biceps characterized by at least partial axonal loss. Also noted was an

underlying peripheral polyneuropathy characterized by sensorimotor

axonal loss and demyelination.

Discussion:

Given its deep location, musculocutanous nerve injuries

are rare but have been reported in athletes performing repetitive

overhead activities as well as a complication of direct trauma,

shoulder dislocations, and surgery. Symptoms include arm pain,

weakness with elbow flexion and/or supination as well as sensory loss

over the lateral aspect of the forearm. Differential diagnoses include

brachial plexopathies and cervical stenosis. Spontaneous recovery is

possible but may take months to years.

Conclusions:

A musculocutaneous nerve injury is an unusual compli-

cation of upper extremity vascular access; given the close proximity of

nerve and vascular structures in the limbs, close monitoring for neu-

ropathy symptoms during and after the procedure is warranted.

Level of Evidence:

Level V

Poster 219:

Male Infertility Treatment Leading to Cerebellar

Cerebrovascular Accident: A Case Report

Hanzla Quraishi, MD (Marianjoy Rehab Hosp)

Disclosures:

Hanzla Quraishi: I Have No Relevant Financial Relation-

ships To Disclose

Case/Program Description:

A 47-year-old man with a past medical

history of asthma, hypertension, and male infertility presented with a

complaint of acute vertigo for 6 days. He stated that it came on suddenly

with concurrent nausea, emesis and diplopia. Brain MRI was positive for

acute right posterior inferior cerebellar artery occlusion and right

vertebral occlusion. He subsequently underwent a midline suboccipital

craniectomy with durotomy and resection of infarcted brain. The pa-

tient was seen by neurology and it was determined that his cerebro-

vascular accident was secondary to hCG injections for male infertility.

Prior to presenting, the patient had no history of atherosclerotic disease

or hypercoagulable state predisposing patient to stroke.

Setting:

Acute Rehabilitation Hospital.

Results:

The patient completed a course of comprehensive inpatient

rehabilitation including physical, occupational, and speech therapies.

Discussion:

There is a known link between spinal cord injury and

stroke with infertility, specifically in the male population. This case

appears to be the first known event of male hCG treatments directly

leading to cerebrovascular accident. Prior cases of hormone therapy

leading to stroke involved either female hormonal therapy or testos-

terone treatment. In the younger rehabilitation population, fertility

and the ability to bear children are a distinct concern of many pa-

tients. Given this, there is merit to educating patients about risks of

fertility therapy as well as monitoring patients actively undergoing

fertility treatment. Comorbidities in the rehabilitation population may

further predispose patients to adverse outcomes regardless of gender.

Conclusions:

Treatment of male infertility can be associated with

increased risk of stroke, even in the absence of testosterone therapy,

specifically with hCG or Clomiphene. Given the biopsychosocial profile

of rehabilitative medicine, fertility concerns can often be of para-

mount importance in this population. Accordingly, it is the re-

sponsibility of the physician to educate patients in regards to risks and

benefits of potential therapy regardless of gender.

Level of Evidence:

Level V

Poster 220:

The Psychosocial Impact of Rehabilitation Services as

Highlighted by the Care of a Patient with Multiple

Epiphyseal Dysplasia: A Case Report

Charles P. Scott, MD (New York Presbyterian Hosp), Nasim Chowdhury, MD

Disclosures:

Charles Scott: I Have No Relevant Financial Relationships

To Disclose

Case/Program Description:

The patient was diagnosed with MED at

age 7 after 2 years of progressive gait impairment. Her father, paternal

uncle, and paternal grandmother were previously diagnosed with MED;

her father and uncle had each undergone bilateral hip replacements.

Neither she, nor her family, has yet undergone genetic testing; all

diagnoses were made clinically with plain film radiographs. She

described feeling increasingly socially isolated as a teenager, largely

due to her inability to participate in activities such as athletics and

casual play, given chronic joint pain and severe fatigue within several

minutes of activity onset. With progressive gait impairments causing

her to limp, she began physical therapy as a young adult, allowing her

to remain independent and to participate in academic, professional,

and social pursuits. After graduating from college, she completed a 26-

month engagement with the Peace Corps in the developing world,

remaining ambulatory with use of a cane. Due to progressive disease

and functional deficits, she underwent bilateral hip replacement at

age 29. Post-operatively, rehabilitation focused on retraining gait

mechanics and increasing independence with household tasks.

Setting:

In-patient rehabilitation unit of a tertiary care hospital.

Results:

The patient made rapid progress with ambulation and func-

tional tasks, and returned to full-time work 45 days after surgery.

Discussion:

Rehabilitation medicine played an integral role

throughout the care of this patient by helping to maintain mobility and

range of motion and through introduction of specific interventions

such as teaching the use of a cane and retraining gait mechanics.

Conclusions:

MED patients face a variety of physical limitations that

may have a marked impact on psychosocial functioning. Rehabilitation

strategies play an integral role in management of MED and can help

patients overcome significant physical barriers to social and profes-

sional integration.

Level of Evidence:

Level V

Poster 221:

Rehabilitation Considerations in a Patient With

Klippel-Feil Syndrome: A Case Report

Grace L. Maloney, MD (Marianjoy Rehab Hosp, Naperville, IL, United

States), Anjum Sayyad, MD

Disclosures:

Grace Maloney: I Have No Relevant Financial Relation-

ships To Disclose

Case/Program Description:

A 55-year-old man with Klippel-Feil syn-

drome, morbid obesity (BMI 47.8), type II diabetes, and asthma

S202

Abstracts / PM R 9 (2017) S131-S290