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Case/Program Description:

A 58-year-old man who suffered a stroke

4 years ago (resulted in mild right hemiparesis with eventual reso-

lution of deficits) presented to his PCP with right lower extremity

pain of 1 year duration. Given the patient’s history of uncontrolled

diabetes (A1c 13%), he was initially treated for diabetic neuropathy

and given gabapentin 300mg TID. Despite this, the patient’s pain

was unabated. He had 5/5 strength in his bilateral lower extremities

and only mildly decreased sensation on the bottom of his feet;

however, he complained of severe, intermittent, sharp, shooting

pain down his right leg to the foot. A lumbar spine MRI revealed

minimal neural foraminal narrowing from L3-S1 bilaterally. A sub-

sequent NCS/EMG revealed mild slowing of right peroneal, tibial and

sural nerves, as well as mildly enlarged MUAPs with reduced

recruitment in right L5 innervated muscles. Patient was determined

to have chronic mild right L5 radiculopathy and his gabapentin was

increased to 600mg TID with only minimal improvement. While

obtaining the patient’s history in our clinic, he mentioned that cold

temperature produced severe pain in his right foot. On examination,

he had allodynia (became tearful upon assessing sensation in right

foot), but did not have asymmetric changes in skin color, temper-

ature or hidrosis. Although brain MRI from 4 years ago was unavai-

lable, repeat brain MRI revealed chronic lacunar infarcts in bilateral

thalami.

Setting:

Outpatient PM&R Clinic.

Results:

The patient was treated with amitriptyline (titrated up to

100 mg daily) for presumed central post-stroke pain with significant

pain relief.

Discussion:

This case highlights the consideration of central post-

stroke pain in patients with severe and not otherwise well-explained

pain status post stroke.

Conclusions:

Although it is helpful for patients to receive an expla-

nation for their pain, there is no definitive cure for central post-stroke

pain, and treatment with neuropathic agents can have a limited

effect.

Level of Evidence:

Level V

Poster 430:

Heterotopic Ossification Treated with Etidronate for

Eight Years

Brittni Micham (UPMC Medical Education PM&R Program, Pittsburgh,

PA, USA), Amanda L. Harrington, MD

Disclosures:

Brittni Micham: I Have No Relevant Financial Relation-

ships To Disclose

Case/Program Description:

A 33-year-old man with a history of

thoracic paraplegia had been started on etidronate 1000mg daily for

left hip heterotopic ossification (HO) in 2007. In 2015, he presented to

clinic for a new patient evaluation. When reviewing his medications, it

was discovered that he had remained on bisphosphonate therapy for

eight years. On exam, he had a large, firm pelvic mass and decreased

range of motion of the left hip. Discussion with the patient’s PCP,

Endocrinologist and previous physiatrist revealed no satisfactory

explanation for continuing bisphosphonate therapy. The patient was

weaned off etidronate by 100mg per week. Immediately after

completing the wean, the patient endorsed decreased range of motion

of the left hip, which was confirmed by his outpatient therapist. CT

scan revealed extensive HO in the pelvic bones and bilateral hips. Bone

scan showed moderately increased uptake in the left iliac bone and hip

suggestive of active bony turnover. The patient was restarted on eti-

dronate 1000mg daily for presumed rebound HO with subsequent

improvement in left hip range of motion.

Setting:

Outpatient clinic.

Results:

Due to risks of long-term bisphosphonate therapy, a more

gradual etidronate wean was initiated decreasing by only 100mg per

month. Four months into the slow taper, he had not yet reported any

further symptomatic progression of HO.

Discussion:

This is the first reported case, to our knowledge, of a

patient on bisphosphonate therapy for HO continuously for several

years. Given the adverse effects of bisphosphonates, treatment for

several years is not recommended. The management of a long-term

bisphosphonate wean in the setting of rebound HO is difficult due to

the lack of literature regarding these topics.

Conclusions:

This case illustrates the importance of reviewing medi-

cations over the course of treatment. The holistic approach encour-

aged in physiatry uniquely positions the field to mitigate risks

associated with medication oversights.

Level of Evidence:

Level V

Poster 431:

Ultrasound Guided Dextrose Prolotherapy with

Platelet Rich Plasma for Sacroiliac Pain: A Case

Report

Glenna Tolbert, MD (Ctr for Rehab and Wellness)

Disclosures:

Glenna Tolbert: I Have No Relevant Financial Relation-

ships To Disclose

Case/Program Description:

We present a case report which dem-

onstrates the successful use of Dextrose- PRP (platelet rich plasma)

spine injection therapy utilizing Hackett’s Method. With the addition

of an ultrasound guided approach to identify the sacroiliac (SI) joint

and ligaments, the procedure was performed safely and accurately

in an office setting [10]. Although ultrasound has limited diagnostic

value in the spine, it aids in identifying target structures and land-

marks. This approach diminishes costs and potential complications

by negating the need for radiological and parenteral analgesia

exposure.

Setting:

Private Practice, Office.

Results:

At 1-year follow-up, the subject maintained pain reduction,

decrease or elimination of pain medications and achievement of

functional goals. Given the preliminary positive outcomes in this

patient with SI pain refractory to myriad treatments, including radio-

frequency ablation, the use of Dextrose-PRP injection therapy

warrants more vigorous investigations.

Discussion:

Sacroiliac (SI) joint pain is commonly associated with

various arthritic conditions. For patients with osteoarthritis (OA)

involving the spine, proper diagnosis, pain management and functional

outcomes remain poor and inconsistent. This is despite widely used

therapies such as steroid and Botulinum Toxin injections, chemo-

nucleolysis, radio-frequency denervation, intradiscal electrothermal

therapy, pain pumps, spinal cord stimulators and surgery [1],[2]. Most

of these options include adverse side effects and significant compli-

cation risks.

Conclusions:

These results suggest an exciting, convenient, and

effective method of managing SI Joint pain, particularly in the geri-

atric population.

Level of Evidence:

Level V

Poster 432:

An Unusual Presentation of Cervical Paraspinal

Denervation Resulting in Neck Drop: A Case Report

Katie Hatt, DO (Temple Univ Hosp, Philadelphia, PA, United States),

Nicholas C. Kinback, MD, Peter Riedel, DO, Michael M. Weinik, DO

Disclosures:

Katie Hatt: I Have No Relevant Financial Relationships To

Disclose

Case/Program Description:

A 82-year-old man presented with acute

onset neck stiffness with neck drop after falling

w

13 steps. He

described difficulty holding his head in the upright position as opposed

to feeling his neck was being pulled forward.

Setting:

Outpatient rehabilitation clinic.

Results:

On examination, the cervical spine was flexed forward. He

was unable to actively extend his neck into neutral. Passively, his neck

S269

Abstracts / PM R 9 (2017) S131-S290