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Objective:

Improving PM&R residents’ ability to teach patients MSK

exercises in the clinic setting. Increase treatment outcomes in an

outpatient PM&R Clinic where physical therapy wait times are over 3

months.

Design:

An educational pamphlet was created under the guidance of a

physical therapist to aid residents in the outpatient setting with

instructing patients on exercises they can perform independently,

without need for equipment. Handouts were made available in clinic

to any patient requiring, but not able to, obtain formal physical

therapy. Pre- and post-test surveys were given to the residents to

assess if the intervention met the stated objectives.

Setting:

Outpatient PM&R Clinic, University Based Academic Medical

Center.

Participants:

PM&R Residents.

Interventions:

1. Resident pamphlet of therapeutic exercises 2. Pa-

tient musculoskeletal exercise handouts.

Main Outcome Measures:

1. Improvement of PM&R resident’s

knowledge of exercises and their ability to teach MSK exercises to

patients. 2. Improvement in patient outcomes in General PM&R

outpatient clinic.

Results:

In the pre-intervention survey, greater than 30% of residents

who consulted PT, had “no idea” what that would entail, 70% had

“somewhat an idea”, and no resident felt completely confident.

Greater than 40% of residents admitted that if patients were not

eligible for therapy, they were simply sent home. In the post-inter-

vention survey, after giving out the resident handouts and making

patient handouts available, positive improvements were seen. Only

15% of residents had “no idea” what PT would entail. The residents

who simply sent patients home without any form of intervention,

dropped from over 40% to 15%. 100% of residents felt the patient

handouts adequately provided good treatment to those patients who

could not get formal physical therapy.

Conclusions:

The objective of improving resident knowledge with

providing exercises to patients with common musculoskeletal disor-

ders was achieved. Residents felt the handouts resulted in the

improvement of quality of care offered in the PM&R clinic.

Level of Evidence:

Level V

CATEGORY: GENERAL REHABILITATION

Poster 476:

Bleeding Events Among Hematologic Inpatient Rehabilitation

Patients with Severe Thrombocytopenia

Jack B. Fu, MD, FAAPMR (UT MD Anderson Cancer Center, Houston,

Texas, United States), Jegy M. Tennison, MD, Isabel M. Rutzen, MD,

Shinichiro Morishita, PhD, Julie K. Silver, MD, FAAPMR, Seyedeh Dibaj,

PhD

Disclosures:

Jack Fu: I Have No Relevant Financial Relationships To

Disclose

Objective:

To identify the frequency and characteristics of bleeding

events during acute inpatient rehabilitation of hematologic malig-

nancy patients with severe thrombocytopenia.

Design:

Retrospective descriptive analysis.

Setting:

National Cancer Institute Comprehensive Cancer Center.

Participants:

All hematologic malignancy patients admitted with a

platelet count of less than or equal to 20,000/microliter on the day of

rehab transfer to the acute inpatient rehabilitation unit from 1/1/2005

through 8/31/2016.

Interventions:

Medical records were retrospectively analyzed for

demographic, laboratory and medical data. Patients were rehabili-

tated using the following institutional exercise guidelines for throm-

bocytopenic patients:

>

20,000/microliter

e

No additional

restrictions. 10,000-20,000/microliter

e

No resistive exercise. If a

high fall risk, avoid standing/ambulating. 5,000-10,000/microliter

e

No resistive exercises and minimal activity (limit the exercises to in

bed or chair).

<

5,000/microliter

e

will discuss with medical team

OR consider deferring treatment.

Main Outcome Measures:

Bleeding events noted in the medical

record.

Results:

135 inpatient rehabilitation admissions of 133 unique patients

were analyzed with a total of 851 inpatient rehabilitation days. The

mean platelet count was 14,000/microliter on the day of admission and

22,000/microliter over the course of the rehabilitation admission. A

total of 98 bleeding events were documented in 77/135 (57%) admis-

sions. Most bleeding events (66/98, 67.3%) were minor and 3/98 (3.1%)

bleeding events were severe enough to require transfer to the primary

acute care service. There were 3/98 (3.1%) bleeding events that were

highly likely attributable to physical activity. However, only 1/3 was

considered severe, requiring transfer to the primary acute care service.

Bleeding rates were .09, .08, .17 and .37 for

>

20,000/microliter,

15-20,000/microliter, 10-15,000/microliter and less than 10,000/

microliter mean platelet counts respectively (P

¼

.003).

Conclusions:

Bleeding rates increased with lower mean platelet

counts. However, using our institutional exercise guidelines for

severely thrombocytopenic patients, the risk of severe bleeding events

in these severely thrombocytopenic hematologic malignancy acute

rehabilitation inpatients was low.

Level of Evidence:

Level III

CATEGORY: MSK & SPORTS MEDICINE

Poster 477:

Clinicians Using Hemoanalytic Data Can Apply the Method of

Ratios to Balance Platelet Concentration Against

Other Cellular Components in Platelet-Rich Plasma

David C. Karli, MD (The Steadman Clinic, Vail, CO, Avon, CO, United

States), Theodore Sand, PhD

Disclosures:

David Karli: Ownership or partnership - Greyledge

Technologies

Objective:

Platelet-rich plasma (PRP) contains positive therapeutic

components [platelets (Plts)] and negative components [red blood cells

(RBCs), white blood cells (WBCs), neutrophils (NEU)]. Past attempts to

categorize PRP samples have relied on binary assessments: RBC andWBC

content above or below 1%, etc. Binary characterization doesn’t help a

clinician balance the level of Plts versus the negative components pre-

sent in PRP. The goal of introducing the method of ratios is to help

standardize and simplify a physician’s assessment of the therapeutic

potential of PRP, allowing greater control in treating patients with PRP.

Design:

Hemoanalytic data from PRP preparations was evaluated to

provide discrete values for Platelet Ratio-RBC (PRR), Platelet Ratio-

WBC (PRW) and Platelet Ratio-NEU (PRN).

Setting:

Method of ratios analysis of PRP preparations was conducted

at a sports medicine clinic.

Participants:

PRP preparations used to treat patients seeking non-

surgical pain relief for soft tissue pathology as a standard of care were

evaluated.

Interventions:

Not applicable.

Main Outcome Measures:

PRR, PRW and PRN were calculated from

hemoanalyticdataobtained on PRPpreparations; data routinely provided

to the attending physician. Each ratio involves dividing the Plt concen-

tration by the concentration of RBCs, WBCs, or NEUs in a patient’s PRP.

Results:

Ratios were calculated for 32 PRP preparations. The mean

(range) of PRR was 16.4 (3.0-77.7), PRW was 361 (12-1443), and PRN

was 3104 (239-24333).

Conclusions:

Method of ratios provides a straight forward comparison

of the number of Plts present per unit RBC, WBC or NEU. Reducing

neutrophils appears to be more efficient compared to WBC reduction

in the assessed PRP preparations, since the average PRN was greater

S284

Abstracts / PM R 9 (2017) S131-S290